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Levitra, Nuviva The efficacy and tolerability of vardenafil, Order levitra a new, oral, selective. phosphodiesterase type 5 inhibitor, in patients with erectile dysfunction the first at-home clinical trialby. Porst H, Rosen R, Padma-Nathan H, Goldstein I, Giuliano F, Ulbrich E, Order levitra Order. levitra Bandel T. Urological Practice, Hamburg, Germany. porst20354 aol. comInt J Impot Res2001 Aug 13 4 192-9 ABSTRACTVardenafil, a novel selective phosphodiesterase type 5. inhibitor, was evaluated in its first large-scale at-home trial. A total of 601 men with mild to severe erectile dysfunction ED were. enrolled Order levitra in this multi-centre, randomized, double-blind, placebo-controlled trial of Levitra dosage 12 weeks. of treatment with either placebo or 5, Order levitra 10 and 20 mg of vardenafil. Primary endpoints were Q3 vaginal penetration and Q4 maintenance of erection . of the International Index of Erectile Function IIEF. In the intent-to-treat population Levitra n 580 , the changes from baseline for 5,. 10 and 20 mg vardenafil 1. 2, 1. 3 and 1.
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scores of 18, 21, 21, for the 5 mg, 10 mg and 20 mg dose. groups, respectively compared to the placebo group EF Domain score of Order levitra. 15. The European trial of 803 subjects confirmed these results. In the North American trial, Levitra significantly improved the rates of achieving an erection sufficient. for penetration SEP2 at doses of 5 mg, 10 mg, and 20 mg. compared to placebo 65 , 75 , and 80 , respectively, compared to a. 52 response in the placebo at 3 months. The European trial confirmed these results. Side EffectsAdverse events associated with the Levitra use of Levitra may include but are. not limited to the following Headache Flushing Rhinitis Dyspepsia Accidental Injury Sinusitis Flu. Syndrome Dizziness Nausea Mechanism of ActionLevitra is a selective inhibitor of cyclic guanosine monophosphate cGMP. -specific phosphodiesterase type 5 PDE5. Erection of the penis is initiated by the relaxation of smooth muscle in the corpus. cavernosum, one of a pair of sponge-like regions in the penis. When aroused, nitric oxide is released from nerve endings Levitra dosage and endothelial cells in. the corpus cavernosum. Nitric oxide activates the enzyme guanylate cyclase resulting in increased synthesis of cyclic guanosine monophosphate. cGMP in the smooth muscle cells of the corpus cavernosum. The cGMP triggers smooth muscle relaxation, increasing blood flow into Elvitra the penis, resulting in. erection. Literature ReferencesBrock G, Nehra A, Lipshultz LI, Karlin GS et al. Safety and efficacy of vardenafil for the treatment of men with erectile dysfunction after radical. retropubic prostatectomy. J Urol.
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